Atypical Antipsychotics (Medical Psychiatry) by John C. Csernansky, John Lauriello

By John C. Csernansky, John Lauriello

Showcasing the most recent experiences within the box, this reference unveils contemporary breakthroughs within the use of peculiar antipsychotics for the therapy of a number of sufferer populations-tracking advancements within the administration of sufferers with schizophrenia and affective psychotic problems, in addition to healing regimens for kids and teenagers.

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Insights into the structure and function of 5-HT2 family serotonin receptors reveal novel strategies for therapeutic target development. Exp Opin Ther Targets 2001; 5:685–695. 5. Revicki DA. Cost effectiveness of the newer atypical antipsychotics: a review of the pharmacoeconomic research evidence. Curr Opin Investig Drugs 2001; 2(1):110–117. 6. Geddes J, et al. Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. Brit Med J 2000; 321(7273): 1371–1376.

44. Kapur S, et al. Is amoxapine an atypical antipsychotic? Positron-emission tomography investigation of its dopamine2 and serotonin2 occupancy. Biol Psychiatry 1999; 45(9):1217–1220. 45. Kapur S, Zipursky RB. Do loxapine plus cyproheptadine make an atypical antipsychotic? PET analysis of their dopamine D2 and serotonin2 receptor occupancy [letter]. Arch Gen Psychiatry 1998; 55(7):666–668. 46. Willins D, Deutch A, Roth BL. Serotonin 5-HT2A receptors are expressed on pyramidal cells and interneurons in the rat cortex.

Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 1975; 188(4194):1217–1219. 18. Creese I, Burt DR, Snyder SH. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 1976; 192(4238):481– 483. 19. Meltzer HY, Matsubara S, Lee J-C. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther 1989; 251:238–246.

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